Dr. Chang’s teaching interests focus on helping students learn Organic Chemistry Lab technique and theories; as well as biotechnology and bioengineering application in real life situation. His goal is to assist all students to reach their highest goals or even more than students thought they could achieve with fun and enthusiasm for Organic and science in general so they can realize a successful life.
Dr. Chang’s research interests center around drug design, synthesis, medical devices, diagnostic kit development, improvement, and clinical trials. He was involved in the R&D of 8-Cl-cAMP which has been through clinical Phase II trials, the Isolex 300i for peripheral stem cell selection (microgenetic stem cell project), and the MaxSept system for bone marrow purging. These have been approved by FDA, European regulatory offices, Japanese regulatory office, along with several other countries in 1997 for the treatments of maladies such as cancer, heart disease, and lung disease. He was also involved in the improvement of blood test systems for fungal allergies, as well as the R&D of several one step diagnostic kits for infectious diseases such as HIV and HCV virus diagnosis. Specific projects currently under his consultation include the development of oral insulin using nanotechnology, a multiple drug anti-cancer project, peripheral stem cell selection and clinical applications, blood separation system development and clinical applications for blood component separation such as platelet collection, removal of antibodies in the blood for the treatment of auto-immune diseases as well as other blood related illness. He has worked with biocompatible surface modification for artificial liver and open heart-lung surgery oxygenator and eye implants, and the clinical applications of enriched oxygen air generated by an Oxygenator for diseases such as Alzheimer disease and other dementia of seniors.
Multiple drugs anti-cancer therapy, Microgenetic peripheral blood stem cells, blood component separation system, nanotechnology for oral insulin/diabetes, biocompatible surface modification for medical devices, and magnetic micro polymer particles for medical and diagnostic devices.