Dr. Surya Nauli

Dr. Surya Nauli

School of Pharmacy
Expertise: Primary Cilium; Vascular Diseases; Polycystic; Kidney Diseases;
Office Location: Rinker Health Science Campus 272
Phone: (714) 516-5485
Minnesota State University-Mankato, Bachelor of Science
Loma Linda University, Ph.D.


Surya Nauli received his doctorate education in Pharmacology from Loma Linda Medical School.  He completed his NIH fellowship at Harvard Medical School followed by his appointment as an Instructor in Medicine.  He then joined the University of Toledo and was promoted to tenured Associate Professor.  In 2014, Dr. Nauli accepted a professor position in the Department of Biomedical & Pharmaceutical Sciences at Chapman University School of Pharmacy.  Specific areas currently under investigation in his laboratory include (1) molecular, cellular, and biophysical studies of primary cilia; (2) chemical screening for pharmacological candidates in vitro; and (3) development of a more efficient in vivo system to further characterize the cilia-targeting therapy in vascular and kidney diseases. 

For inquiry, please visit  http://sites.chapman.edu/nauli/

Research Interests 

Main Research Area includes:

  • Cilia Biology
  • Cardiovascular Disease
  • Polycystic Kidney Disease

Recent Creative, Scholarly Work and Publications

Doerr N, Wang Y, Kipp KR, Liu G, Benza JJ, Pletnev V, Pavlov TS, Staruschenko A, Mohieldin AM, Takahashi M, Nauli SM, Weimbs T. Regulation of Polycystin-1 Function by Calmodulin Binding. PLoS One. 2016 Aug 25;11(8):e0161525.
Sherpa RT, Atkinson KF, Ferreira VP, Nauli SM. Rapamycin increases length and mechanosensory function of primary cilia in renal epithelial and vascular endothelial cells. Int Educ Res J. 2016 Dec;2(12):91-97.
Atkinson KF, Nauli SM. pH sensors and ion Transporters: Potential therapeutic targets for acid-base disorders. International Journal of Pharma Research & Review. 2016 March 01; 5(3):51-58.
Kathem SH, AbouAlaiwi WA, Zi X, Nauli SM. Capillary Endothelia from Two ADPKD Patients are Polyploidy. Annals of clinical cytology and Pathology. 2016 April 25; 2(2):1022.
Grimes DT, Keynton JL, Buenavista MT, Jin X, Patel SH, Kyosuke S, Vibert J, Williams DJ, Hamada H, Hussain R, Nauli SM, Norris DP. Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination. PLoS Genet. 2016 Jun 6;12(6):e1006070.
Nauli SM, Pala R, Kleene SJ. Calcium channels in primary cilia. Curr Opin Nephrol Hypertens. 2016 Sep;25(5):452-8.
Mohieldin AM, Zubayer HS, Al Omran AJ, Saternos HC, Zarban A, Nauli SM, AbouAlaiwi WA. Vascular Endothelial Primary Cilia: Mechanosensation and Hypertension. Curr Hypertens Rev. 2016;12(1):57-67.
Aal-Aaboda M, Alhaddad H, Osowik F, Nauli SM, Sari Y. Effects of (R)-(-)-5-methyl-1-nicotinoyl-2-pyrazoline on glutamate transporter 1 and cysteine/glutamate exchanger as well as ethanol drinking behavior in male, alcohol-preferring rats. J Neurosci Res. 2015 Jun;93(6):930-7.
Mohieldin AM, Haymour HS, Lo ST, AbouAlaiwi WA, Atkinson KF, Ward CJ, Gao M, Wessely O, Nauli SM. Protein composition and movements of membrane swellings associated with primary cilia. Cell Mol Life Sci. 2015 Jun;72(12):2415-29.
Patel S, Garapati C, Chowdhury P, Gupta H, Nesamony J, Nauli S, Boddu SH. Development and evaluation of dexamethasone nanomicelles with potential for treating posterior uveitis after topical application. J Ocul Pharmacol Ther. 2015 May;31(4):215-27.
Atkinson KF, Kathem SH, Jin X, Muntean BS, Abou-Alaiwi WA, Nauli AM, Nauli SM. Dopaminergic signaling within the primary cilia in the renovascular system. Front Physiol. 2015 Apr 16;6:103.
Al Omran AJ, Saternos HC, Liu T, Nauli SM, AbouAlaiwi WA. Live Imaging of the Ependymal Cilia in the Lateral Ventricles of the Mouse Brain. J Vis Exp. 2015 Jun 1;(100):e52853.
Mohieldin AM, AbouAlaiwi WA, Gao M, Nauli SM. Chemical-Free Technique to Study the Ultrastructure of Primary Cilium. Sci Rep. 2015 Nov 2;5:15982.
The cell’s antenna; sensory roles of primary cilia: ciliopathy and ciliotherapy. International Innovation. January 2015. Issue 170, page 98