The IACUC at Chapman is implementing protocol-processing software by Cayuse. Meanwhile, please continue to use the two-part form process, which can be found in the Forms and Links tab.
More information to come.
User authentication is a process within the Cayuse software. It is not yet implemented. More information to come.
Meanwhile, all personnel working with animals on a protocol - research or teaching - must complete appropriate training and be enrolled in the LAOHP. The PI is responsible for including them on the protocol - thru the initial submission and in later amendments.
The review is initiated when receipt of a complete protocol application or amendment, including all required documents, is accepted by the IACUC Administrator. Protocol approval is required at least every three (3) years. Protocols requiring Institutional Biosafety Committee (IBC) approval must obtain it prior to IACUC approval. Principal Investigators (PIs) are strongly encouraged to consult with the campus veterinarian during the planning stages and prior to protocol submission, particularly for studies that have significant potential for pain or distress. Experts from within or outside the University community or consultants may be asked to assist in review of protocols that are complex in nature.
The IACUC Chair will receive the accepted protocol from the IACUC Administrator and will recommend one of two review methods: Designated Member Review (DMR) or Full Committee Review (FCR).
Designated Member Review (DMR)
A copy of the written protocol is sent to all IACUC committee members via email. Any member of the committee may request a FCR within 5 business days if they deem it necessary. Following a FCR request, a full committee meeting must convene with a properly constituted quorum. If no requests for FCR are received, the IACUC Chair will appoint one qualified committee member, along with the committee’s veterinarian, to head the review process as the Designated Member Reviewer (DMR).
The DMR has the following options:
- Approve the protocol or amendment if all criteria are met and satisfied
- Request revision(s) to the protocol or amendment if outstanding issues are present in order to secure approval
- Request FCR when further review of the protocol or amendment is warranted
Full Committee Review (FCR)
Full Committee Meetings are schedule monthly according to the above calendar.
The following outcomes of a FCR may occur:
- Approval by majority affirmative vote
- Revisions requested to secure approval
- Defer or table review of protocol if more clarification or outside consultation is needed
- Withhold approval of protocol if it has not adequately addressed all requirements necessary
If the IACUC is unable to approve a protocol, the PI is notified with a detailed report of the requested revisions.
Modifications to an Approved Protocol:
Investigators who desire to make modifications (also called amendments) to an approved protocol during the approval period, must submit a modification for approval prior to initiating the change. Modifications include administrative changes such as addition or deletion of research personnel, as well significant changes such as modifications to the study design or objectives, the number of animals or species used, increases in pain or distress, changes to therapeutic or experimental agents or changes in euthanasia methods. Approval of a modification does not change the existing protocol expiration date.
Investigators who plan to submit an animal use protocol must submit an application at least four weeks prior to the intended start date to allow sufficient time for committee review. Student Investigators must have a faculty member or academic professional staff serve as an advisor on his or her project and the protocol must be submitted under the advisor's name.
Full Committee Reviews occur once a month and the protocol must be submitted to the IACUC office by the 5th of the month for review at that month's review date. See schedule below.
(on or around) December 5, 2017January 5, 2018
February 5, 2018
March 5, 2018
April 5, 2018
May 5, 2018
June 5, 2018
July 5, 2018
August 5, 2018September 5, 2018
(at the IACUC meeting scheduled)to be determinedDecember 13, 2017January 24, 2018February 28, 2018March 28, 2018April 25, 2018May 23, 2018June 27, 2018July 25, 2018August 29, 2018September 26, 2018