» NMR Research Core Facility

Welcome to the NMR Research Core Facility of School of Pharmacy at the Chapman University. We offer a variety of services to researchers from the Chapman University and for external users. We can provide training and advise researchers how to use NMR spectrometer efficiently. We also can run experiments requested by users.

Fee: Researchers and students of Chapman University have free access to the NMR Spectrometer.

For outside users, current base rates are $20/proton and $50/carbon experiment (tube and solvent included, see details here).

Our facility is equipped with 400 MHz Bruker NMR spectrometer.

  • 5 mm broadband observe (BBO) probe:
    • 1H (outer coil); 15N-31P and 19F (inner coil).
  • Prodigy broadband observe CryoProbeTM:
    • 1H/19F (outer coil); 15N-31P (inner coil).
  • Z-axis pulsed field gradient capability.
  • Autosampler for automated analysis of up to 24 samples.

+ - General rules and requirements:

  • Chapman researchers can use the spectrometer for their own educational or research projects without the charge.
  • Students, assistants, and postdocs, who would like to use the spectrometer, should provide written request from their PI (Chapman University faculty).
  • All users should demonstrate sufficient proficiency in operating the spectrometer. User training is available upon request.
  • All users can analyze their samples with the room-temperature BBO (broadband observe) or Prodigy CryoProbeTM. Please contact Dr. Maslennikov in advance if you need to use the CryoProbe.
  • Please do not bring any radioactive samples – we will not allow to analyze them in any circumstances.
  • If you would like to ask us to measure your samples the flat rates (including tubes and solvents) for internal users are $8/sample for 1D proton and $20/sample for 1D carbon experiments. Please see this page for other rates.
  • All self-service users should provide their own tubes, caps, and NMR-compatible solvents. We recommend Norell 508-UP-7 / Wilmad SP528 or better tubes for quantitative analysis and Norell SVCP-5-178 or better tubes for HTP experiments.
  • Other rules for sample preparation:
    • Use PTFE caps for volatile solvents.
    • Do not use broken tubes and/or damaged caps.
    • Solvent/sample length in the NMR tube: minimum 4 cm, maximum 5 cm.
    • If your tube broke accidently in the magnet, let us know immediately and do not try to recover the tube – the probe can be damaged.
  • If you want to use special tubes, please let us know in advance.
  • We can provide you with appropriate HTP NMR tubes and caps if you return them clean and undamaged.
  • The facility can provide necessary equipment for sample preparation (pipette samplers, tips, hand centrifuge for NMR tubes) and temporary storage (+4C, -20C).
  • If you need any additional equipment to handle your samples, please bring it with you or let us know in advance.

+ - Current Rates for NMR Spectroscopy Services

Internal users self-service: Free of charge.

Internal and External users non-self-service (rates per sample):

 

Chapman University

Academia and not-for-profit

For-profit
organizations

Remarks

Standard 1D-NMR

1H

$8

$10

$20

 

13

≥4mg

$20

$25

$50

MW <2,000 Da,

1H 1D-spectrum included

<4mg

$40

$70

$150

19F

$20

$25

$50

 

31P

$20

$25

$50

 

Other

$30/hour

$40/hour

$80/hour

Please contact us

Homo & Hetero
2D-NMR

$30/hour

$40/hour

$80/hour

Maximum charge 3h/sample

Diffusion 1H

$30

$40

$80

 

Other NMR experiments

Please contact us

 

Spectra Interpretation

$100/hour

Please contact us

+ - Acknowledgement of Facility

In case you used the data collected in our Facility for publication, please add an acknowledgement for the facility assistance. Thank you.

Contact

Dr. Innokentiy Maslennikov

Research Assistant Professor, NMR Facility Coordinator

Phone: (714)-516-5448

Email: maslenni@chapman.edu