Some of the content on this website requires JavaScript to be enabled in your web browser to function as intended. This includes, but is not limited to: navigation, video, image galleries, etc. While the website is still usable without JavaScript, it should be enabled to enjoy the full interactive experience.
»
Dr. Marcia Abbott
Assistant Professor
Crean College of Health and Behavioral Sciences; Health Sciences and Kinesiology
Schmid College of Science and Technology; Chemistry
School of Pharmacy
- Office Location:
- Crean Hall 136
- Office Hours:
- Tuesday and Thursday 11:30am-2:30pm
- Phone:
- (714) 516-6157
- Email:
- mabbott@chapman.edu
- Education
- Ohio University, Bachelor of Science
Miami University, Master of Science
University of Southern California, Ph.D.
- Biography
Dr Marcia Abbott completed her doctoral work at the University of Southern California (USC) in Los Angeles, CA in the Integrative and Evolutionary Biology Graduate Program. Dr Abbott’s research focused on the role of exercise and skeletal muscle contraction on fatty acid metabolism. Following graduation Dr Abbott joined the Sul Lab at the University of California (UC), Berkeley in the Department of Nutritional Sciences and Toxicology, as a post doctoral fellow. While at UC Berkeley, she carried out studies aimed at examining to role of lipases in regulation of obesity and insulin secretion. Following her time as at UC Berkeley, Dr Abbott accepted a position as a Research Scholar in the Endocrine Research Unit, VA Medical Center, UC San Francisco. Her work at UCSF focused on the examination of potential regulators of mesenchymal stem cell commitment towards adipocyte lineages. In 2013, she joined the faculty in the Department of Kinesiology at San Francisco State University.
In 2014, Dr Abbott joined Chapman University in the Crean College of Health and Behavioral Sciences as an Assistant Professor. She is pursuing studies aimed at examining the role of skeletal muscle and its relation to obesity. Overall, Dr Abbott hopes to contribute to the growing body of research aimed at preventing and/or treating obesity.
Teaching:
- BIOL/HESC 366
- HESC 350/350L
Research Interests:
- Molecular regulators of obesity and related metabolic disorders
- Understanding the role of exercise in regulating secretion of hormones originating in the skeletal muscle (myokines)
- Discovering novel activators of brown adipose tissue
Memberships
- American Physiological Society
- The Obesity Society
- The American College of Sports Medicine
- Recent Creative, Scholarly Work and Publications
-
Wang L, Roth T, Abbott MJ, Ho L, Wattanachanya L, and Nissenson RA. Osteoblast-derived FGG9 regulates skeletal homeostasis. Bone, 98:18-35, 2017.
-
Kim SJ, Tang T, Abbott MJ, Viscarra JA, Wang Y, Sul HS. AMPK Phosphorylates Desnutrin/ATGL and Hormone-Sensitive Lipase To Regulate Lipolysis and Fatty Acid Oxidation within Adipose Tissue. Mol Cell Biol, 36:1961-76, 2016.
-
Thornton SM*, Krolopp JE*, and Abbott MJ. IL-15 mediates mitochondrial activity through a PPARd-dependent-PPARa-independent mechanism in skeletal muscle cells. PPAR Research, 2016. *Chapman University students
-
Krolopp JE*, Thornton SM*, and Abbott MJ. IL-15 Activates the Jak3/STAT3 Signaling Pathway to Mediate Glucose Uptake in Skeletal Muscle Cells. Frontiers in Physiology, 7:626, 2016. *Chapman University students
-
Abbott MJ, Roth TM, Ho L, Wang L, O’Carroll D, and Nissenson RA. Negative Skeletal Effects of Locally Produced Adiponectin. PLoS One, 10(7): e0134290, 2015.
-
Abbott MJ and Turcotte LP. AMPKa2 is involved in exercise training-induced adaptations in insulin-stimulated metabolism in skeletal muscle following high fat diet. J Appl Physiol. 117:869-79, 2014.
-
Kao RS, Abbott MJ, Louie A, O'Carroll D, Lu WD, and Nissenson RA. Constitutive protein kinase A activity in osteocytes produces an anabolic effect on bone. Endocrine. 55:277-87, 2013.
-
Wattanachanya L, Lu W-D, Kundu RK, Wang L, Abbott MJ, O’Carroll D, Quertermous T, and Nissenson RA. Increased bone mass in mice lacking the adipokine apelin. Endocrinology, 154:2069-80, 2013.
-
Tang T*, Abbott MJ*, Ahmadian M, Lopes AB, Wang Y, Sul HS. Desnutrin/ATGL activates PPARd to promote mitochondrial function for insulin secretion in islet ß cells. Cell Metabolism, 18:883-97, 2013. *these authors contributed equally to this work
-
Abbott MJ, Constantinescu S, and Turcotte LP. AMPKa2 is an essential signal in the regulation of insulin-stimulated fatty acid uptake in control-fed and high fat-fed mice. Exper Physiol. 97:603-17, 2012.
-
Turcotte LP and Abbott MJ. Contraction-induced signaling: Evidence of convergent cascades in the regulation of muscle fatty acid metabolism. Canadian J Physiol and Pharmacol. 90:1419-1433, 2012.