The use of vertebrates by a member of the Chapman University research community requires approval of Chapman's Institutional Animal Care & Use Committee (IACUC). The IACUC is charged with evaluating the scientific merit of the experiment with the ethical costs to the animals. The committee must ensure that the experiment causes the least possible pain, distress, discomfort and morbidity to the animal, in regards to the animal's sentiency and scientific merit of the experiment.
The IACUC is a self-regulating entity that, according to U.S. federal law, must be established by institutions that use laboratory animals for research or instructional purposes. The procedures of the IACUC must comply with a variety of requirements issued by federal, state and local governments and non-governmental organizations.