Dr. Viet-Huong Nguyen

Dr. Viet-Huong Nguyen

Associate Professor, Pharmacy Practice
School of Pharmacy
Expertise: Epilepsy; Stroke; Genetics; Neuropharmacology; Epidemiology;
Office Location: Rinker Health Science Campus 221
Phone: 714-516-5417
Education:
University of Southern California, Bachelor of Arts
University of California, Los Angeles, Master of Public Health
University of Southern California, Master of Science
University of California, San Francisco, Doctor of Pharmacy

Biography

Dr. Nguyen received her Bachelor of Arts degree in Biology and Classics with an emphasis in Literature and Mythology from the University of Southern California in 2001.  She went on to receive her Master of Science degree in Cell and Neurobiology from the University of Southern California in 2003, where she studied molecular signaling pathways of the central nervous system.  She received her Doctor of Pharmacy degree from the UCSF School of Pharmacy in 2007.  While at UCSF, she began to apply her neuroscience background to clinical and translational research and was awarded a fellowship grant from the American Foundation of Pharmaceutical Education (AFPE) to study the role of drug transporters and pharmacogenetics in drug resistant epilepsy.  She completed a general practice pharmacy residency as well as an additional two-year specialty practice residency/fellowship in Neurology at the VA Greater Los Angeles Healthcare System (VAGLAHS), where she expanded her research in pharmacogenetics and drug resistance to include mechanisms of pharmacoresistance in status epilepticus.  In 2014, she received her Master of Public Health degree in Epidemiology from UCLA with a research emphasis in study design and genetic epidemiology. 

Prior to joining CUSP, Dr. Nguyen served as the Clinical Pharmacist Specialist in Neurology at the VAGLAHS’s Epilepsy Center of Excellence.  She also served as the Stroke Pharmacist/ Coordinator for the Stroke program at VAGLAHS and was responsible for the implementation of numerous innovative pharmacy services, including the development of an Anti-Epileptic Drug Response Phenotype Database as well as the development of pharmacist-managed Epilepsy and Stroke Prevention clinics with expanded scope of practice.  Additionally, she was integral to the development of the PGY2 specialty pharmacy practice residency in Neurology at VAGLAHS, the first neurology pharmacy residency eligible for ASHP accreditation.  She was also an Adjunct Assistant Professor of Pharmacy Practice at USC School of Pharmacy for 8 years, assisting with the curriculum for epilepsy and stroke and has mentored/precepted over 80 students and residents from VAGLAHS, USC, UCSF, UOP, and Western University Schools of Pharmacy.

Research Interests:

Dr. Nguyen’s research interests are in the areas of epilepsy and stroke.  She is interested in the pharmacogenetics of drug response and resistance in epilepsy and is a member of GENESS, an international consortium of clinicians and scientists whose mission is to identify genes causing genetic epilepsies including Juvenile Myoclonic Epilepsy, Childhood Absence Epilepsy, and Lafora Epilepsy,in order to develop curative therapies for these disorders.  Dr. Nguyen also participates in stroke outcomes/health services research and has authored numerous peer-reviewed publications, book chapters, and meeting abstracts in epilepsy, stroke, and neuropharmacy.

Recent Creative, Scholarly Work and Publications

Nguyen V-H, Dergalust S, Chang E. (2023). Epilepsy. In DiPiro JT, Yee GC, Posey LM, Haines ST, Nolin TD, Ellingrod V (Eds.), Pharmacotherapy: A pathophysiologic approach, 12th Edition (pp. 877-912). New York, NY: McGraw Hill Education
Nguyen V-H, Bainbridge J, Dergalust S. (2022). Pharmacist roles in interprofessional team care of people with epilepsy and approach to care. In J Engel, T Pedley, J Aicardi, MA Dichter, S Moshe, MR Trimble (Eds.), Epilepsy: A Comprehensive Textbook (pp. 1421-28). Philadelphia, PA: Wolters Kluwer/Lippincott Williams & Wilkins.
Nguyen V-H and Dergalust S. (2021). Traumatic Brain Injury. In Pharmacotherapy Self-Assessment Series Neurology Psychiatry (pp. 151-182). Lenexa, KS: American College of Clinical Pharmacy.
Nguyen V-H, Dergalust S, Chang E. (2020). Epilepsy. In JT Dipiro, GC Yee, M Posey, ST Haines, TD Nolin, & V Ellingrod (Eds.), Pharmacotherapy: A pathophysiologic approach, Eleventh Edition (pp. 877-912). New York, NY: McGraw Hill Education.
Delgado-Escueta AV, Nguyen V-H, Duron RM, Bailey JN, Serratosa JM. Genetic basis and testing of epileptic syndromes. (2019). In M Bureau, P Genton, AV Delgado-Escueta, C Dravet, R Guerrini, CA Tassinari, P Thomas, P Wolf (Eds.), Epileptic Syndromes in Infancy, Childhood, and Adolescence, 6th Edition (pp. 7-36). John Libby Eurotext Ltd.
Nguyen V-H and Dergalust S (2019). Epilepsy. In PharmacotherapyFirst: A multimedia learning resource; First Edition. Washington, DC: APhA Publications.
Dergalust S and Nguyen V-H. (2019). Antiepileptic Drugs: First Generation. In A Hussain & ET Tran (Eds.), Department of Veterans Affairs Epilepsy Manual, 2nd Edition (pp. 133-154). San Francisco, CA: Epilepsy Centers of Excellence, Department of Veterans Affairs.
T Munyer, M Hunter, R Hoover, WC Mobley, A Jacobson, D Kisor, M Benrashid, K Cardone, BI Crouch, S Dergalust, DR Fasanella, TD Gladwell, R Greene, K Klinker, E Law, S Luttrell, S Miller, V-H Nguyen, B Reed, CJ Rollins, K Sando… KJ Tietze (Eds.). (2019) Pharmacotherapy First: A multimedia resource; First Edition. Washington, DC: APhA Publications.
Discua D, Duron RM, Nguyen V-H, Garrido C, Delgado-Escueta AV Using Data Mining Tools, Microservices Architecture And Artificial Intelligence Modules For The "Juvenile Myoclonic Epilepsy JME-1000 Project"". Neurology. 2019;92(Suppl 15):P4.656.
Silva R, Duron RM, Flores W, Siriani Y, Nguyen V-H, Tanaka M, Delgado-Escueta AV. Progressive Myoclonus Epilepsy of Lafora First Diagnosed in El Salvador. Neurology. 2019;92(Suppl 15):P4.578.
Rao NM, Wu MJ, Nguyen V-H, Dergalust S, Aramian A, Minassian G, Siddiqui U, McCreary M, Neil WP, Wallis RA, Saver JL. Multicenter Analysis of Stroke Risk Factor Treatment. Stroke. 2018;49(Suppl 1):WP281.
Discua D, Duron RM, Martinez IE, Nguyen V-H, Patterson C, Bailey JN, Tanaka M, Ochoa A, Jara Prado A, Alonso M, López Ruiz M, Medina M, Guilhoto L, Yacubian E, Silva R, Arias C, Delgado-Escueta A. A New Database Platform for Clinical and Genetic Investigation of Epilepsies and the New ILAE Classification. Neurology. 2018;90(Suppl 15):P2.261.
Tanaka M, Martinez-Juarez I, Duron RM, Nguyen V-H, Ochoa A, Jara-Prado A, Alonso M, Lopez-Ruiz M, Medina M, Guilhoto L, Yacubian M, Silva R, Patterson C, Bailey J, Delgado-Escueta A. Autophagy in Juvenile Myoclonic Epilepsy (JME). Neurology. 2018;90(Suppl 15):P2.275.
Durón RM, Arias C, Martínez-Juárez I, Patterson C, Bailey J, Tanaka M, Ochoa A, Jara-Prado A, Alonso M, Medina M, Nguyen V-H, Delgado-Escueta AV. Analyzing Phenotypes Using Artificial Intelligence Tools in Subgroups of Absence and Myoclonic Epilepsies. Neurology, 2018;90(Suppl 15):P.2.344.
Bailey JN, de Nijs L, Bai D, Suzuki T, Miyamoto H, Tanaka M, Patterson C, Lin YC, Medina MT, Alonso ME, Serratosa JM, Durón RM, Nguyen V-H, Wight JE, Martínez-Juárez IE, Ochoa A, Jara-Prado A, Guilhoto L, Molina Y, Yacubian EM, Lopez-Ruiz M, Inoue Y, Kaneko S, Hirose S, Osawa M, Oguni H, Fujimoto S, Grisar T, Yamakawa K, Lakaye B, Delgado-Escueta AV. Intestinal Cell Kinase heterozygous variants in Juvenile Myoclonic Epilepsy. New England Journal of Medicine. 2018;378:1018-1028.
Nguyen V-H, Baca CB, Chen JJ, Rogers SA. (2017). Epilepsy. In JT Dipiro, R Talbert, GC Yee, GR Matzke, & BG Wells (Eds.), Pharmacotherapy: A pathophysiologic approach, Tenth Edition (pp. 837-866). New York, NY: McGraw Hill Education.
Cook AM, Liang N, Nguyen V-H. (2017) Antiepileptic agents for the prevention and treatment of seizures. In G Brophy (Eds), Updates in Neurocritical Care, First Edition (pp.219-242). New Brunswick, NJ: Rutgers University Press.
Nguyen V-H, Duron RM, Serratosa JM, Minassian B, Michelucci R, Genton P, Sinha S, Arabi M, Beydoun A, Ben-Menachem E, Kecmanovic M, Guilhoto L, Whitehouse W, Salas-Puig J, Martinez-Juarez I, Gentry M, Bailey J, Delgado-Escueta AV. (2017). Clinical Center for the Lafora Epilepsy Cure Initiative (LECI): Clinical trial readiness for a global curative drug trial (P2.245). Neurology. 2017;88(Suppl 16):P2-245.
Nguyen V-H, Serratosa JM, Gonzales B, Genton P, Michelucci R, Sinha S, Chandra S, Beydoun A, Arabi M, Kecmanovic M, Whitehouse W, Martinez-Juarez IM, Guilhoto L, Salas-Puig J, Ben-Menachem E, Goldsmith D, Duron RM, Medina MT, Bailey JN, Gentry M, Minassian B, Delgado-Escueta AV. Updates to the Lafora Epilepsy Cure Initiative (LECI) Clinical Center: Development of a data collection tool for measurement of Lafora Epilepsy Disease Progression. Epilepsia. 2017;58(Suppl 5):S194-S195.
Amirrad F, Bousoik E, Shamloo K, Al-Shiyab H, Nguyen VV, Montazeri-Aliabadi H. Alzheimer’s Disease: Dawn of a New Era? Journal of Pharmacy and Pharmaceutical Sciences. 2017;20:184 - 225.
Duron R, Medina M, Martínez-Juarez I, Jara-Prado A, Ochoa A, Lopez-Ruiz M, Molina Y, Guilhoto L, Yacubian E, Wight J, Nguyen VH, Lin Y, Bai D, Tanaka M, Patterson C, Alonso ME, Bailey JN, Delgado-Escueta AV. Absence Seizures in Juvenile Myoclonic Epilepsy: Whole Exome Sequencing Results and Subsyndromes (P2. 008). Neurology. 2016;86(Suppl 16):P2-008.
Nguyen VH, Wen MM, Clarito LA, Bukovskaya Y, Minassian GL, Panizzon K, Dergalust S, Wallis RA. Abstract WP327: Implementation of a Pharmacist Driven Comprehensive Stroke Education Program. Stroke. 2016;47(Suppl 1):AWP327.
Nguyen VH, Wong BM, Shen DD, Woo DT, Vu AV, & Lie JD. Early Management of Acute Ischemic Stroke: Focus on IV tPA and Timely Reperfusion. US Pharm. 2016;41(1)HS9-HS12.
Wight JE, Nguyen VH, Medina MT, Patterson C, Durón RM, Molina Y, Lin YC, Martínez-Juárez IE, Ochoa A, Jara-Prado A, Tanaka M, Bai D, Aftab S, Bailey JN, Delgado-Escueta AV. Chromosome loci vary by juvenile myoclonic epilepsy subsyndromes: linkage and haplotype analysis applied to epilepsy and EEG 3.5–6.0 Hz polyspike waves. Molecular genetics & genomic medicine. 2016;4(2):197–210.
Bailey JN, Patterson C, de Nijs L, Durón RM, Nguyen VH, Tanaka M, Medina MT, Jara-Prado A, Martínez-Juárez IE, Ochoa A, Molina Y, Suzuki T, Alonso ME, Wight JE, Lin YC, Guilhoto L, Yacubian EMT, Jesús Machado-Salas J, Daga A, Yamakawa K, Grisar TM, Lakaye B & Delgado-Escueta AV. EFHC1 variants in juvenile myoclonic epilepsy: reanalysis according to NHGRI and ACMG guidelines for assigning disease causality. Genetics in Medicine. 2016;19:144-156.
Nguyen VH, Roger BA, Dergalust S, Wasterlain CG. Time-dependent effects of lacosamide, ketamine, and combination ketamine and diazepam treatment in a rat lithium-pilocarpine model of status epilepticus. Epilepsia. 2015;56(Suppl 1):258.

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