Dr. Melissa A. Rowland-Goldsmith
Assistant Professor, Instructional Faculty
- Office Location:
- Crean Hall 207 ( 501 W. Palm Ave )
- (714) 744-7892
- Chapman University, Bachelor of Science in Chemistry/Biology
University of California, Riverside, Ph.D. in Biochemistry
Through my unique teaching style, I have the opportunity to change countless students’ lives by introducing them to a varied and holistic approach to the study of molecular biology. The outcomes of many of my students are representative of what can be seen from using many unique and special teaching methods. Several former students have told me that my courses helped to prepare them for graduate or professional schools. Though I certainly do not know the outcomes or career path of every student I have taught, I know that of the biology and biochemistry majors I have counseled, mentored, or taught, more than ten have started or completed medical, dental school, PA or NP programs, several have started or completed Ph.D. programs, and a few have started or completed Masters programs. Several former research students are currently enrolled in Ph.D. programs and have continued in cancer research. These former students want to pursue an academic career.
My laboratory focuses on studying human pancreatic cancer which is the 4th leading cause of cancer related death in the United States. The ability of pomegranate juice extract (PJE) to stimulate apoptosis (programmed cell death) and inhibit cancer cell invasion in several cancer types has been attributed to its high polyphenol content. Since decreased pancreatic cancer patient survival is correlated with evasion of apoptotic pathways and changes in the extracellular matrix, we initially hypothesized that treatment of human pancreatic cancer cells with PJE would promote apoptosis and cell adhesion associated proteins. Currently, my lab is studying the molecular mechanism involved in promoting apoptosis in pancreatic cancer cells treated with PJE. We are also assessing the pomegranate phytochemical effects on pancreatic cancer cell cycle arrest. It is my sincere desire to continue these teaching and research endeavors at Chapman for many years to come.
BIOL 208 Introduction to Molecular Genetics and Cell Biology
BIOL 209 Introduction to Molecular Genetics and Cell Biology Laboratory
BIOL 436 Molecular Genetics
- Recent Creative, Scholarly Work and Publications
Rowland-Goldsmith M.A. (2012) author of power-point lectures (chapter’s 1 through 4) for Thieman and Palladino’s Introduction to Biotechnology, 3rd edition textbook, Benjamin Cummings Publishing, San Francisco, CA
Akahoshi,L., Berrigan,E., Boone,M., Chesne,R., James,C., Lawless,N., Punton,S., Singh,H., Swinford,N., Zylstra,A. and Rowland-Goldsmith,M. (2011) Jacaranda mimosifolia glyceraldehyde-3-phosphate dehydrogenase (GAPC-1) gene, partial cds. GenBank accession #JF440302.1 http://www.ncbi.nlm.nih.gov/nuccore/JF440302.1
Gomez V., Shackelford T., Tocchi A., Rowland-Goldsmith M.A. (2010). ”The effect of pomegranate juice extract on the Hedgehog signaling pathway in pancreatic cancer.” Chapman University e-Research: A Journal of Undergraduate Work. 1 (2).
Rowland-Goldsmith M.A. (2009). “Laboratory exercises: A new way to introduce microarray technology in a lecture/ laboratory setting by studying the evolution of this modern technology.“ Biochemistry and Molecular Biology Education. 37 p 37-43.
Moss M., Rowland-Goldsmith M.A., Sawant L., Fahy M. (2009). “Mutant X - a bioinformatics exercise for undergraduate biology students.” Computational Science Education Reference Desk (CSERD), a Pathways project of the National Science Digital Library.
Rowland-Goldsmith M.A., McNulty N., Krause J. (2009). ” Microarray Data Analysis: Can Significance Save Your Life?” Computational Science Education Reference Desk (CSERD), a Pathways project of the National Science Digital Library.
Justice,M.S., Kjelland,J.D., Minardi,C.S., Nguyen,A.A., Orellana,D., Perkins,C.M., Rowland-Goldsmith,M.A. (2009). Linum usitatissimum glyceraldehyde-3-phosphate dehydrogenase (GAPC2) gene, partial cds. GenBank accession #:GQ148916.1 http://www.ncbi.nlm.nih.gov/nuccore/GQ148916.1